Health-related Quality of Life in Patients Undergoing Ileal Ureter Replacement for Extensive Ureteral Stricture: A Prospective Multi-institutional Study.

ABSTRACT:

Background and objective

Ileal ureter replacement (IUR) is the definitive management approach for extensive ureteral strictures (UrSs). Patients with UrS exhibit poor health-related quality of life (HRQoL). We conducted a long-term, multi-institutional evaluation of patients who underwent IUR to assess its durable safety and efficacy, as well as postoperative recovery of HRQoL.

Methods

A prospective multicenter study (January 2020-July 2022) enrolled patients with an extensive UrS scheduled for IUR. Participants completed the 36-item Short Form Survey (SF-36) before and at 6 mo and 12 mo after surgery. A significant HRQoL improvement was defined as an increase of ≥10 points from baseline.

Key findings and limitations

Overall, 82 consecutive patients who underwent IUR

SUBMITTER: Wang X 

PROVIDER: S-EPMC12860627 | biostudies-literature | 2026 Mar

REPOSITORIES: biostudies-literature