Sexual Toxicity After Chemoradiation for Anal Cancer Among Men Who Have Sex With Men: A Mixed-Methods Analysis.

ABSTRACT:

Purpose

Chemoradiation (CRT) is the standard of treatment for localized anal squamous cell carcinoma (SCCA). Although cure rates are high, acute and late toxicities are common. There are increasing published data regarding vaginal stenosis and erectile dysfunction; however, the nature and impact of holistic sexual dysfunction after pelvic radiation, particularly among men who have sex with men (MSM), remains poorly characterized. This study aimed to: (1) explore patient-reported sexual health outcomes among MSM as measured by existing patient-reported outcome tools, and (2) assess the applicability of these existing tools for this population.

Methods and materials

MSM who are at least 6 months out from completion of CRT for SCCA were recruited via fliers and online platforms

SUBMITTER: Gold BO 

PROVIDER: S-EPMC12860787 | biostudies-literature | 2026 Mar

REPOSITORIES: biostudies-literature