Relationship between duration of intraoperative hypotension and postoperative delirium in patients undergoing head and neck cancer surgery with free flap reconstruction: a retrospective observational study.

ABSTRACT:

Purpose

Postoperative delirium (POD) is a frequent complication after surgery, especially in elderly patients undergoing head and neck cancer surgery with free flap reconstruction. This study aimed to assess the associations between intraoperative hypotension (IOH), its duration, and occurrence of POD.

Methods

This retrospective study included 239 patients aged 65 years or older who underwent head and neck cancer surgery with free flap reconstruction. IOH was defined at seven mean arterial pressure (MAP) thresholds, ranging from 55 to 85 mmHg, in 5 mmHg increments. The duration of each IOH was compared between patients with or without POD before and after initiation of microsurgery. Multivariate analysis was conducted to assess the independent association of each IOH duratio

SUBMITTER: Obata N 

PROVIDER: S-EPMC12860842 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature