The stability of pain phenotypes in people with hand osteoarthritis - results from the NOR-HAND study.

ABSTRACT:

Objective

In a hand osteoarthritis (OA) cohort, we aimed to explore pain phenotypes and characterize their stabilities using the multidimensional framework developed by The Initiative on Methods, Measurement and Pain Assessment in Clinical Trials (IMMPACT).

Methods

We included participants attending the visits at baseline (2016-17) and follow-up (2019-21) in the Nor-Hand study. To identify pain phenotypes (i.e., classes), we conducted latent transition analyses modelling self-reported pain severity, neuropathic-like pain, fatigue, sleep, anxiodepressive symptoms, pain catastrophizing, and quantitative sensory testing (QST). We compared a model including QST with a model without. Longitudinal stability of classes was assessed. Changes in indicator variables across participant

SUBMITTER: Bordvik DH 

PROVIDER: S-EPMC12861019 | biostudies-literature | 2026 Mar

REPOSITORIES: biostudies-literature