The n-3 PUFA content of the global lipidomes of NIST SRM 2378, SRM 1950, and intralaboratory quality control materials.

ABSTRACT: The regular use of commercially available Standard Reference Materials (SRM) and intralaboratory quality control materials, which are important tools, is essential for standardizing and ensuring high-quality lipidomic analyses. These materials should also be relevant for the research application. To support nutritional lipidomic research, the global lipidome of materials derived from individuals consuming a range of n-3 PUFAs was determined. Nontargeted lipidomics were completed on SRM 2378 (serum), SRM 1950 (plasma), and intralaboratory quality control (plasma) generated from individuals with low omega-3 and high omega-3 status. SRM 2378 includes materials generated from individuals consuming fish oil (SRM 2378-1), flaxseed oil (SRM 2378-2), and no supplements (SRM 2378-3). Specific lipid

SUBMITTER: Stark KD 

PROVIDER: S-EPMC12861023 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature