Steatotic liver disease and liver transplantation: Candidate selection and post-transplant management.

ABSTRACT: Steatotic liver disease (SLD), which encompasses alcohol-related liver disease (ALD), metabolic dysfunction-associated steatotic liver disease (MASLD), and MASLD with increased alcohol intake (MetALD), is now the leading cause of liver transplantation (LT) worldwide. ALD and MASLD have become the first and second leading indications for LT (41% and 12% in Europe, respectively), with MetALD accounting for a rapidly increasing proportion of transplants (8-10%). Candidate evaluation must be multidisciplinary and account for the complex interplay between alcohol use, metabolic syndrome, cancer, cardiovascular disease, and obesity. Early LT for severe alcohol-related hepatitis is an established option in selected patients after the evaluation of alcohol use disorder (AUD) by addiction specialis

SUBMITTER: Colmenero J 

PROVIDER: S-EPMC12861030 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature