Rheumatoid arthritis and stroke risk: a systematic review and meta-analysis.

ABSTRACT:

Objectives

This meta-analysis aims to evaluate the association between rheumatoid arthritis (RA) and stroke risk. Methods: PubMed, Cochrane Library, and Embase were searched for observational studies published from database inception to October 7, 2025, using medical subject headings (MeSH) and keywords. Random effect models were used to calculate odds ratios (OR) and 95% confidence intervals (CI) for evaluating the associations between RA and stroke risk. All statistical analyses were performed using Stata statistical software version 17.0. The funnel plot, Egger's test and Begg's test were used to evaluate publication bias.

Results

This meta-analysis included 12 observational studies with a total of 1,715,001 participants, published between 2003 and 2025. The pooled analys

SUBMITTER: Yang L 

PROVIDER: S-EPMC12861136 | biostudies-literature | 2026

REPOSITORIES: biostudies-literature