Functional Brain Activity Associated With Intermittent Rhythmic Delta/Theta Activity: A Transdiagnostic Electroencephalography-Functional Magnetic Resonance Imaging Resting-State Study.

ABSTRACT:

Background

Intermittent rhythmic delta/theta activity (IRDA/IRTA) detected via electroencephalography (EEG) has been implicated in the pathophysiology of neuropsychiatric illnesses. Therefore, a combined EEG and functional magnetic resonance imaging (fMRI) approach was applied in a transdiagnostic group of patients with different causalities, i.e., autoimmune-mediated (in suspected autoimmune psychiatric syndromes [APS]) and primary psychiatric (borderline personality disorder [BPD]) causalities, as well as in healthy control (HC) participants, to characterize the brain regions functionally correlated with IRDA/IRTA.

Methods

Overall, 135 EEG-fMRI datasets met the quality criteria, including 33 patients with suspected APS, 59 cases with BPD, and 43 HC participants. fMRI data

SUBMITTER: Feige B 

PROVIDER: S-EPMC12861157 | biostudies-literature | 2026 Mar

REPOSITORIES: biostudies-literature