Implanted Miniature Light Devices for Phototherapeutics.

ABSTRACT: Light-mediated healthcare has several very attractive features, including minimally invasive administration, reduced possibility of side effects, and potential for patient-specific treatment. However, the shallow penetration of light into skin and tissue is an inherent physical limitation that restricts the use of phototherapy to superficial sites of disease. To mitigate this major problem, researchers and clinicians are developing miniature light devices that can be implanted at strategic deep-tissue locations within a living subject. The work is leveraged by emerging new classes of light-absorbing drugs and light-activated drug delivery methods. This Perspective summarizes the major concepts and recent technical advances in this interdisciplinary subfield of advanced phototherapeutics. F

SUBMITTER: Sanders HS 

PROVIDER: S-EPMC12861309 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature