AOSNP-ADAPTR resource level-based recommendations on practical diagnostic strategies for WHO CNS5 adult-type diffuse gliomas.

ABSTRACT: The fifth edition of the WHO classification of CNS Tumors (WHO CNS5) has revised the diagnostic and grading criteria for Adult-type Diffuse Gliomas (ADGs) by integrating molecular parameters with histologic features. Conducting molecular testing for most ADGs is now crucial in fulfilling the WHO CNS5 diagnostic criteria. However, due to additional costs and technical barriers, implementing molecular diagnostics is often not feasible in Low-Income Countries (LICs) and Lower Middle-Income Countries (LMICs). Therefore, practical approaches are needed for diagnosis in resource-restrained settings. Hence, the Asian Oceanian Society of Neuropathology (AOSNP), through the 'ADAPTR' (Adapting Diagnostic Approaches for Practical Taxonomy in Resource-Restrained Regions) initiative, aimed to provide r

SUBMITTER: Santosh V 

PROVIDER: S-EPMC12861567 | biostudies-literature | 2026 Mar

REPOSITORIES: biostudies-literature