Clinical Course and Autopsy of a 70-Year-Old Woman With Double-Inlet Left Ventricle.

ABSTRACT:

Background

Survival to adulthood with an unrepaired double-inlet left ventricle is rare and typically associated with pulmonary stenosis, which provides protective hemodynamic effects.

Case summary

We report a 70-year-old woman with an unrepaired double-inlet left ventricle without pulmonary stenosis, the longest documented instance of this condition. She presented with mild symptoms (NYHA functional class I and II) and underwent pharmacological treatment for chronic heart failure. Six months later, she developed pulmonary thromboembolism and died of respiratory failure. Postmortem examination revealed significant atherosclerosis as well as hypertensive changes of the pulmonary vasculature.

Discussion

The absence of pulmonary stenosis may have contributed to progressi

SUBMITTER: Murakawa K 

PROVIDER: S-EPMC12861618 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature