Pulmonary Tumor Thrombotic Microangiopathy With Biventricular Heart Failure.

ABSTRACT:

Background

Pulmonary tumor thrombotic microangiopathy (PTTM), a rare and often fatal condition characterized by tumor cell embolization within pulmonary arterioles, is frequently diagnosed using pulmonary artery aspiration cytology. PTTM is associated with poor prognosis.

Case summary

A 51-year-old woman with ovarian cancer presented with biventricular heart failure and reduced left ventricular ejection fraction. Right heart catheterization showed a mean pulmonary artery pressure of 34 mm Hg, consistent with combined pre- and postcapillary pulmonary hypertension. Despite these findings, pulmonary artery aspiration cytology confirmed the diagnosis of PTTM. The patient showed clinical improvement after heart failure management and chemotherapy.

Discussion

This case high

SUBMITTER: Mihara Y 

PROVIDER: S-EPMC12861619 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature