Coronary Angioscopy and Optical Coherence Tomography Assessment of the Pathophysiology of Intraplaque Hemorrhage.

ABSTRACT:

Background

Histologically, intraplaque hemorrhage (IPH) is a recognized cause of acute coronary syndrome. However, the in vivo lesion characteristics of IPH and mechanisms leading to acute coronary syndrome remain unclear.

Case summary

A 77-year-old woman presented with chest pain at rest or on light exertion and new electrocardiographic changes. Cardiac computed tomography angiography demonstrated significant stenosis with the napkin-ring sign in the left anterior descending artery. Preintervention optical coherence tomography (OCT) revealed heterogeneous signal-poor regions with delineated borders and a white thrombus. Coronary angioscopy showed reddish plaque with an exposed red thrombus and adjacent white thrombus. OCT after excimer laser coronary angioplasty demonstrate

SUBMITTER: Kimura S 

PROVIDER: S-EPMC12861623 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature