Modern Management of Massive Pulmonary Emboli and Concurrent Grade III Splenic Laceration.

ABSTRACT:

Background

Pulmonary embolism (PE) is a leading cause of cardiovascular mortality. Active hemorrhage complicates management by limiting the use of thrombolytic therapy.

Case summary

A 59-year-old woman presented after a syncopal episode and fall. Imaging revealed massive bilateral PE and a grade III splenic laceration. Standard anticoagulation and thrombolysis were contraindicated. The Pulmonary Embolism Response Team (PERT) guided care, including catheter-directed thrombectomy with significant hemodynamic improvement, followed by splenic artery coil embolization. An inferior vena cava filter was placed while anticoagulation was temporarily withheld. Once stabilized, anticoagulation was resumed, and the filter was later removed. The patient achieved full recovery during foll

SUBMITTER: Farrow-Cypel BK 

PROVIDER: S-EPMC12861651 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature