Factors associated with pathologic myopia onset and progression: A systematic review and meta-analysis.

ABSTRACT:

Purpose

To synthesise evidence across studies on factors associated with pathologic myopia (PM) onset and progression based on the META-analysis for Pathologic Myopia (META-PM) classification framework.

Methods

Findings from six longitudinal studies (5-18 years) were narratively synthesised and meta-analysed, using odds ratio (OR) as the common measure of association. All studies adjusted for baseline myopia, age and sex at a minimum. The quality of evidence was rated using the Grades of Recommendation, Assessment, Development and Evaluation framework.

Results

Five out of six studies were conducted in Asia. There was inconclusive evidence of an independent effect (or lack thereof) of ethnicity and sex on PM onset/progression. The odds of PM onset increased with greate

SUBMITTER: Yii F 

PROVIDER: S-EPMC12862026 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature