The Prognostic Value of Capillary Refill Time in Patients With Sepsis: A Prospective Cohort Study.

ABSTRACT:

Background

Sepsis is life-threatening due to organ dysfunction from a dysregulated host response. Despite macrohemodynamic stabilisation, microcirculatory disturbances may persist. Capillary refill time (CRT) is a simple bedside indicator of microcirculatory perfusion, but its dynamic prognostic value over time is underexplored.

Aim

To observe CRT changes in sepsis patients and evaluate its predictive value at different time points.

Study design

This prospective cohort study enrolled sepsis patients receiving bundle therapy at a single centre. Patients were grouped by 28-day survival. Baseline data, CRT, lactate (Lac) and central venous pressure (CVP) were measured at eight time points (pre-treatment to 72 h) compare inter-group and intra-group differences. Spearman's

SUBMITTER: Ma L 

PROVIDER: S-EPMC12862114 | biostudies-literature | 2026 Mar

REPOSITORIES: biostudies-literature