Vascular uptake on 18F-FDG PET/CT predicts relapse in new-onset PMR.

ABSTRACT:

Objective

In this study, we utilize 18F-fluorodeoxyglucose (FDG) PET/CT to assess vascular involvement in patients with PMR, aiming to clarify its role in identifying subclinical GCA and its potential association with disease relapse.

Methods

We conducted a retrospective cohort study of 80 patients diagnosed with PMR who underwent PET/CT scanning at Ruijin hospital from September 2015 to December 2023. Based on PET/CT findings, patients were divided into two groups: those with vascular involvement and those without. We compared baseline clinical characteristics, treatments and relapse rates between the two groups. Multivariate Cox regression analysis was performed to identify independent predictors of relapse.

Results

In our cohort, 14 patients (14/80, 17.5%) were ide

SUBMITTER: Dai N 

PROVIDER: S-EPMC12862371 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature