The transcriptional regulatory network of the Escherichia coli MG1655 reference strain.

ABSTRACT: The growth of RNA sequencing (RNA-seq) data accompanied by the development of novel scalable data analytic methods has revealed a deep understanding of the composition of bacterial transcriptomes. This new, first-biological-principles understanding has enabled a novel characterization of the function of the transcriptional regulatory network. Here, we present a single-strain wild-type transcriptomic knowledgebase for the model strain Escherichia coli MG1655. The associated transcriptomic compendium consists of 584 high-quality RNA-seq samples from wild-type E. coli MG1655 generated using a single protocol. These samples range over a wide condition space, including 45 carbon sources and 10 base media. Using independent component analysis, we decomposed the transcriptomic compendium to extra

SUBMITTER: Bajpe H 

PROVIDER: S-EPMC12862375 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature