Quality of Life in Prostate Cancer Patients Following Radical Prostatectomy: A Systematic Review and Meta-Analysis.

ABSTRACT:

Objective

Quality of life (QoL) is a key outcome for assessing the effectiveness of treatment and surgical techniques. Radical prostatectomy (RP) impacts QoL in both psychological and physical aspects. This systematic review and meta-analysis aim to evaluate QoL changes in prostate cancer patients before and after RP.

Methods

PubMed, EMBASE, and the Cochrane Central Register were searched for studies on PCa patients undergoing RP, with QoL assessed using EORTC QLQ-C30 and/or QLQ-PR25 questionnaires before and one year after surgery. Primary outcomes included overall QoL with open and laparoscopic robotic/hand-assisted RP. Secondary outcomes covered emotional, social, and sexual functioning, urinary symptoms, and pain. Statistical analysis was performed using Review Manager 5

SUBMITTER: Seputra KP 

PROVIDER: S-EPMC12862406 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature