Pretreatment CRP-Albumin-Lymphocyte (CALLY) Index as a Prognostic Biomarker of Survival and Recurrence-Free Survival in Patients With Early-Stage Cervical Cancer After Radical Hysterectomy: A Multicenter Retrospective Cohort Study.

ABSTRACT:

Introduction/background

The C-reactive protein (CRP)-albumin-lymphocyte (CALLY) index is a new prognostic biomarker combining CRP, serum albumin, and lymphocyte count that can be associated with the survival of cancer patients by assessing immune, nutritional, and inflammatory status as an important immune indicator. The association of CALLY index as a marker predicting survival of cancer patients with cervical cancer (CC) remains unclear. This study aimed to evaluate the prognostic value of the CALLY index with overall survival (OS) and recurrence-free survival (RFS) in patients with early-stage CC after radical hysterectomy.

Methodology

In this multicenter retrospective cohort study, we examined the medical profile of 806 women with early-stage CC who underwent Type II/III

SUBMITTER: Bahardoust M 

PROVIDER: S-EPMC12862499 | biostudies-literature | 2026

REPOSITORIES: biostudies-literature