Utilization and discontinuation of secondary prevention pharmacotherapy after myocardial infarction: a nationwide cohort study.

ABSTRACT:

Aims

To analyse utilization and discontinuation of secondary preventive medications after acute myocardial infarction (MI).

Methods and results

In separate analyses for each drug [statins, beta-blockers, aspirin, and renin-angiotensin-aldosterone system (RAAS) inhibitors], patients with a first-time MI (2006-2021) registered in the nationwide Swedish MI register SWEDEHEART, surviving >30 days, and discharged with a new prescription of the drug were included. Based on filled prescriptions, treatment initiation, discontinuation (defined as ≥90-day period of non-treatment after the end of previous prescriptions), reinitiation (restarting treatment after discontinuation), and the proportion of patients with ongoing treatment at various time points after the MI were assessed. The

SUBMITTER: Yari A 

PROVIDER: S-EPMC12862975 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature