Diabetic peripheral neuropathy as measured using a point-of-care sural nerve conduction device is associated with a faster decline in renal function in patients with type 2 diabetes.

ABSTRACT:

Aims/introduction

Diabetic peripheral neuropathy (DPN) is a common complication of diabetes mellitus and may be linked to renal function decline. However, the prognostic value of point-of-care nerve conduction devices such as DPN-Check® for renal outcomes remains unclear.

Materials and methods

We conducted a single-center retrospective observational study of 403 patients with diabetes (median follow-up 2.9 years) at Tokyo Metropolitan Ohkubo Hospital. DPN was assessed by DPN-Check® (amplitude [AMP] <5 μV or nerve conduction velocity [NCV] <42 m/s) and simplified diagnostic criteria (SDC). The primary outcome was annual eGFR decline, calculated by the linear least squares method; rapid decliners were defined as those with a decline ≥5 mL/min/1.73 m²/year. Multivari

SUBMITTER: Fukuda T 

PROVIDER: S-EPMC12862999 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature