Country-level and global burden of diseases caused by group A <i>Streptococcus:</i> protocol for a multicountry epidemiological study.

ABSTRACT:

Introduction

Group A Streptococcus (Strep A) causes a wide spectrum of diseases, ranging from pharyngitis and impetigo to severe invasive infections and immune-mediated conditions such as acute rheumatic fever, rheumatic heart disease and acute post-streptococcal glomerulonephritis. Contemporary data on the global burden of Strep A diseases are lacking. The proposed study aims to use administrative data from numerous jurisdictions to estimate age-specific incidence or prevalence of Strep A diseases, with an emphasis on severe clinical endpoints. Depending on the availability of data, a secondary objective will be to estimate the economic burden of Strep A diseases.

Methods and analysis

This population-based descriptive study will use routine health data obtained from

SUBMITTER: Taye BW 

PROVIDER: S-EPMC12863330 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature