Virological failure and risk factors among people living with HIV taking second-line ART in Addis Ababa, Ethiopia.

ABSTRACT:

Background

Virological failure (VF) presents significant challenges in the emergence of drug resistance, and elevated risk of transmission, higher mortality rates, and a diminished quality of life. Various factors contribute to VF, but documented information on this issue is lacking in Ethiopia. Therefore, this study aimed to assess the prevalence of VF and identify the risk factors among people living with HIV who are on second-line antiretroviral treatment (ART).

Methods

A concurrent mixed-method study using quantitative and qualitative data was conducted at selected hospitals in Addis Ababa, Ethiopia. The analysis was conducted using SPSS version 28, Stata version 18.5, and R for quantitative data and thematic analysis with Atlas.ti version 24 software was used for qualit

SUBMITTER: Feyissa BB 

PROVIDER: S-EPMC12863470 | biostudies-literature | 2026

REPOSITORIES: biostudies-literature