Relationship between lactate-to-albumin ratio and all-cause mortality among critically ill pediatric patients: Results from the pediatric intensive care database.

ABSTRACT:

Background

The lactate-to-albumin ratio (LAR) has emerged as a valuable prognostic marker in adult critically ill patients. However, evidence regarding its association with mortality in pediatric intensive care unit (ICU) patients remains limited. The present study utilized data from the Pediatric Intensive Care (PIC) database to investigate the relationship between LAR and clinical outcomes among critically ill pediatric patients.

Methods

This study enrolled 4,162 pediatric patients from the PIC database as study participants. A piecewise multivariate Cox regression model was constructed, incorporating subgroup analysis and restricted cubic spline (RCS) curve analysis, to investigate the association between the LAR and all-cause mortality during hospitalization and ICU stay

SUBMITTER: Zuo X 

PROVIDER: S-EPMC12863524 | biostudies-literature | 2026

REPOSITORIES: biostudies-literature