Nucleolar protein 6 as a potential oncogenic factor in colorectal cancer.

ABSTRACT:

Background

Colorectal cancer (CRC) is a common malignancy of the digestive tract associated with high mortality rates and significant invasive properties. Despite advancements in research, a comprehensive understanding of the regulatory mechanisms underlying CRC remains elusive.

Objective

This study aimed to investigate the potential role of nucleolar protein 6 (NOL6) and its related genes as novel biomarkers for cell proliferation in CRC. The findings of this study could significantly contribute to early diagnosis and more effective therapeutic strategies for CRC.

Methods

Human CRC cell line HCT116 was cultured under standard conditions. Quantitative real-time polymerase chain reaction and immunohistochemistry analysis were used to measure NOL6 expression levels in C

SUBMITTER: Song S 

PROVIDER: S-EPMC12863548 | biostudies-literature | 2026

REPOSITORIES: biostudies-literature