Assessment of Sublingual Microcirculation to Evaluate the Efficacy of Resuscitation Therapy in Septic Shock Patients: A Cohort Study.

ABSTRACT:

Objectives

Determining the endpoint of resuscitation in septic shock is essential to enhance effectiveness, prevent over-resuscitation, and improve outcomes. We designed this study to investigate whether sublingual microcirculation monitoring can serve as an effective marker for assessing the efficacy of resuscitation therapy in septic shock.

Methods

A total of 72 septic shock patients were included in our final analysis, excluding those with heart function impairments, including sepsis-induced cardiomyopathy. Sublingual microcirculation parameters were measured at two time points: before resuscitation and 6 hours postresuscitation. Additionally, the values of macrocirculatory parameters, blood gas analysis variables, and organ prognosis indicators were collected at multiple

SUBMITTER: Zhang X 

PROVIDER: S-EPMC12863597 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature