Epidemiological links of HIV-1 CRF01_AE among MSM in Northern Vietnam and Japan.

ABSTRACT:

Objectives

The bidirectional increase of visitors between Vietnam and Japan has raised concerns about the spread of CRF01_AE; however, the epidemiological characteristics of CRF01_AE in Vietnam and its relationship with Japan remain unclear. We compared the CRF01_AE gene sequences from Vietnam and Japan to understand their epidemiolocal relationships.

Design

A molecular-epidemiological observational study.

Methods

We analyzed 753 protease--reverse transcriptase sequences from CRF01_AE-infected individuals in northern Vietnam and 500 CRF01_AE sequences from the Japanese Drug Resistance HIV-1 Surveillance Network's cluster database. We inferred the chronological phylogeny of these sequences with HIV-1 subtype references and identified statistically significant Vietnam-r

SUBMITTER: Shiino T 

PROVIDER: S-EPMC12863627 | biostudies-literature | 2026 Mar

REPOSITORIES: biostudies-literature