Impact of microvascular invasion on clinical outcomes in hepatocellular carcinoma patients following liver transplantation.

ABSTRACT: This study aimed to investigate the influence of microvascular invasion (MVI) on the prognosis of hepatocellular carcinoma (HCC) patients after liver transplantation. We retrospectively analyzed the clinicopathological data of 130 HCC patients who underwent liver transplantation in First People's Hospital of Foshan, Foshan, China between January 2011 and October 2024. Cox regression analysis was employed to determine whether MVI is an independent prognostic factor for patient survival. Survival analysis was also performed. Among the 130 patients, 39 (30.0%) patients had MVI. Patients with MVI had significantly worse postoperative survival compared to those without MVI (P = .0486). The 1-, 3-, and 5-year survival rates for patients with MVI were 69.23%, 30.77%, and 28.21%, respectively, whi

SUBMITTER: Yan Q 

PROVIDER: S-EPMC12863788 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature