The Role and Efficacy of NovoSorb Biodegradable Temporizing Matrix in Complex Reconstructive Wounds: A Systematic Review.

ABSTRACT:

Background

Managing complex wounds with exposed bone, tendons, metalware, or irradiated tissue is challenging. NovoSorb Biodegradable Temporizing Matrix (BTM) offers an alternative by promoting vascularization and neodermis formation. This review assessed the effectiveness of BTM in managing complex wounds, including those with vascular compromise (eg, periosteal stripping or denuded paratenon) or exposure to radiotherapy.

Methods

A systematic search of Embase, Ovid, Scopus, and PubMed was conducted. Inclusion criteria included wounds involving exposed bone, tendons, or radiotherapy exposure. Data were analyzed for clinical outcomes, demographic variables, and complications.

Results

A total of 208 patients across 34 studies were analyzed. The overall complication rate

SUBMITTER: Shadid OH 

PROVIDER: S-EPMC12863789 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature