Association between adjunctive corticosteroid therapy and clinical outcomes in children with severe viral community-acquired pneumonia: A retrospective cohort study.

ABSTRACT: The therapeutic role of corticosteroids (CS) in severe community-acquired pneumonia (CAP) remains contentious, particularly in pediatric populations with viral etiology. Limited pediatric-specific evidence exists regarding CS efficacy in viral CAP, despite widespread clinical utilization. This retrospective cohort analysis examined the association between adjunctive CS therapy and clinical outcomes in children with severe viral CAP. A retrospective cohort analysis was conducted at a tertiary pediatric intensive care unit from January 2016 to December 2019. Inclusion criteria comprised positive viral pathogen detection following the 2011 Pediatric Infectious Diseases Society/Infectious Diseases Society of America severity criteria. The primary outcome was in-hospital mortality. Secondary ou

SUBMITTER: Zuo Y 

PROVIDER: S-EPMC12863870 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature