Acellular Dermal Matrix-Associated Recurrent Capsular Contracture in a Breast Augmentation Patient.

ABSTRACT: Capsular contracture (CC) is a common complication following breast augmentation. Acellular dermal matrix (ADM) is increasingly used to reduce and treat CC in breast augmentation. However, rare cases of ADM-associated CC can occur. In this case report, we describe a 63-year-old breast augmentation patient who developed significant recurrent CC following subglandular augmentation, capsulectomies, and ADM-assisted revisions. Despite ADM coverage, the patient developed Baker grade 3 CC. Histologic and immunohistochemical analyses were performed on capsular tissue adjacent to visible ADM (study ADM) and on capsule without ADM contact (study capsule), and the results were compared with benign controls. Study ADM demonstrated histologic evidence of ADM resorption and increased fibrotic density.

SUBMITTER: Petrecca S 

PROVIDER: S-EPMC12863915 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature