HoloSimR: a comprehensive framework for simulating breeding programs including the hologenome scenario.

ABSTRACT: Including microbiome information in breeding schemes may be helpful to improve the selection response of livestock populations. However, the complexity of the microbiome makes modeling across species and traits difficult. The estimation of the microbiability and the identification of the microbial species are highly dependent on the methodology used. Indeed, it is complicated to decide which is the best method because we fail to know the true underlying scenario. This study proposes an R package named HoloSimR for simulating the coevolution of the genome and the microbiota under a selection process. HoloSimR allows the user to explore the effect of the microbiota on the phenotypic response to selection and the effects of the environment, host genetics, and symbiosis between microbial speci

SUBMITTER: Casto-Rebollo C 

PROVIDER: S-EPMC12863939 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature