Overnight-dwelled amino acid-based peritoneal dialysis solutions for malnutrition in CAPD: a prospective real-world study.

ABSTRACT:

Purpose

To assess the efficacy and safety of amino acid peritoneal dialysis (AA-PD) in improving nutritional status among continuous ambulatory peritoneal dialysis (CAPD) patients with malnutrition in a real-world setting.

Methods

A prospective self-control study was conducted across five hospitals in China. Patients aged 18-75 years with malnutrition [serum albumin < 35 g/L, prealbumin < 300 mg/L, or Subjective Global Assessment (SGA) score > 7] were enrolled. Each patient used one bag of 2 L 1.1% AA-PD solution to replace the 1.5% dextrose solution for the overnight dwell. All patients received routine nutritional management at their respective centers. Primary outcomes were changes in serum albumin and prealbumin levels. Secondary outcomes included SGA, normalized protein

SUBMITTER: Deng S 

PROVIDER: S-EPMC12864266 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature