Single-center experience with immune checkpoint inhibitor-related ureteritis and cystitis.

ABSTRACT:

Backgroud

Ureteritis and cystitis is a rare immune-related adverse event (irAE) of immune checkpoint inhibitors (ICIs), challenging to distinguish from urinary tract infection (UTI), easily leading to missed diagnosis. We aim to describe clinical features, radiological characteristics and treatment of patients who suffer from ICI-related ureteritis and cystitis (ICI-UC).

Methods

This was a single centre case series of patients diagnosed with solid tumor who received ICIs treatment and subsequently suffered from ICI-UC. All clinical demographic data, laboratory parameters, imaging characteristics, and treatment information were collected.

Results

Between Mar 1^st, 2020 and Mar 31^th 2025, 12 of 1239 patients treated at Peking Union Medical College H

SUBMITTER: Wang C 

PROVIDER: S-EPMC12864438 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature