Anti-inflammatory and cancer chemopreventive potential of essential oils from some cultivated plants in Egypt.

ABSTRACT: This study aimed to investigate the biological activity of essential oils (EOs) of Artemisia abrotanum, Lavandula dentata, Cymbopogon citratus and Laurus nobilis as anti-inflammatory and cancer chemopreventive activities. The anti-inflammatory activity was evaluated using lipopolysaccharides-induced nitric oxide (NO) inhibition on murine macrophage cells (RAW264.7) and cancer chemo-preventive influence was assessed in vitro utilizing Hepa1c1c7 murine carcinoma cells. The EO of A. abrotanum has the most potential activity toward inhibition of NO release, recording 96.6 ± 0.1%, as estimated by Greiss assay. Followed by EOs of L. dentata and L. nobilis with 63.6 ± 0.11 and 37.0 ± 0.23%, respectively. At the protein expression level, western blotting technique was used to evaluate the expressi

SUBMITTER: Ali MI 

PROVIDER: S-EPMC12864766 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature