Approach Motivation and Reward Sensitivity: Effects of High-Definition Transcranial Direct Current Stimulation (HD-tDCS) to Brain Hemispheres on Effort-Related Cardiovascular Response.

ABSTRACT: This study examined the effect of brain hemisphere stimulation on effort intensity. We applied high-definition transcranial direct current stimulation (HD-tDCS) to the dorsolateral prefrontal cortex (dlPFC) to manipulate left or right hemispheric activity and assess its impact on cardiovascular responses reflecting effort. In total, 102 participants (65 women, 37 men) performed a mental concentration task under right cathodal, left cathodal, or sham stimulation conditions. We recorded cardiovascular responses, including pre-ejection period (PEP), systolic blood pressure (SBP), heart rate (HR), and diastolic blood pressure (DBP). Preregistered hypotheses predicted right cathodal stimulation to lead to greater left frontal hemispheric activity. This should result in higher effort during a me

SUBMITTER: Framorando D 

PROVIDER: S-EPMC12865145 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature