Lifestyle Change After Initial Colonoscopy Screening and Incidence of Colorectal Cancer and Major Chronic Diseases.

ABSTRACT:

Introduction

The impact of lifestyle changes after colorectal cancer (CRC) screening on risk of CRC and major chronic diseases remains unknown.

Methods

Leveraging the repeatedly collected dietary, lifestyle, and screening data in the Nurses' Health Study (1988-2018), Nurses' Health Study II (1993-2019) and Health Professionals Follow-up Study (1988-2016), we assessed changes after initial colonoscopy screening in a healthy lifestyle score (0-5) based on smoking, body mass index, physical activity, alcohol intake, and diet. We used time-varying multivariable Cox regression to calculate hazard ratios (HRs) and 95% confidence intervals (CIs) for incidence of CRC and major chronic diseases (including cancer, cardiovascular disease, and type 2 diabetes), among 118,396 and 88,558

SUBMITTER: Knudsen MD 

PROVIDER: S-EPMC12865775 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature