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ABSTRACT: Background
Subclinical hypothyroidism (SCH) is a common condition during pregnancy that can be treated with levothyroxine at a dosage of 0.5-1 mcg/kg/day. If left untreated, the risk of hypertensive disorders of pregnancy increases. However, we did not find any studies examining the impact of levothyroxine on blood pressure levels in pregnancy. Therefore, we decided to assess blood pressure levels in pregnant women with SCH who are using levothyroxine, as well as in euthyroid subjects.Materials and methods
This prospective cohort study involved 245 primiparous women. The mean systolic blood pressure (SBP) and diastolic blood pressure (DBP) were collected from pregnancy records at weeks 6-10, 18, 26, 33, 36, and 37-41. Using generalized estimating equations, we analyzed the
SUBMITTER: Halili A
PROVIDER: S-EPMC12867184 | biostudies-literature | 2025
REPOSITORIES: biostudies-literature