Integration sites of <i>bla</i> _CTX-M-1 relate to IncI1 plasmid phylogeny in <i>Salmonella</i> isolates from non-human sources in Germany.

ABSTRACT: Antimicrobial resistance to cephalosporins in Enterobacterales is commonly mediated by extended-spectrum β-lactamases (ESBL). The ESBL-encoding gene most frequently detected in Salmonella isolates from livestock and the second most frequently detected in Salmonella isolates in humans in Germany is the bla _CTX-M-1 gene. In this study, we characterize ESBL-producing Salmonella enterica collected from non-human sources in Germany, with a particular focus on bla _CTX-M-1 harboring IncI1 plasmids. Therefore, a total of 95 bla _CTX-M-1 positive isolates (S. Derby, S. Infantis, and S. Typhimurium/1,4,[5],12:i:-) from food and animal origin were investigated using short and long-read Whole-Genome S

SUBMITTER: Atxaerandio-Landa A 

PROVIDER: S-EPMC12868207 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature