Genome-wide characterization of histone deacetylases in <i>Fusarium proliferatum</i>: phylogeny, structure, and stress responses.

ABSTRACT:

Background

Fusarium proliferatum, a globally distributed phytopathogen causing destructive root rot in economically vital crops, employs epigenetic mechanisms to adapt to environmental conditions.

Results

Our genome-wide characterization identified eight histone deacetylase (FpHDACs) genes phylogenetically classified into RPD3/HDA1 and Sirtuin subfamilies. Comprehensive genomic characterization revealed two distinctive features: expanded domain architectures exemplified by the Arb2domain within Fp_HDA1, and subcellular localization prediction indicates-where most FpHDACs reside cytoplasmically under neutral pH, but undergo nuclear translocation in alkaline environments. Evolutionary diversification occurred principally via subfunctionalization rat

SUBMITTER: Shi HM 

PROVIDER: S-EPMC12869994 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature