Clinical Manifestations of Emerging Trichosporon spp. Infections, France.

ABSTRACT: Fungi in the family Trichosporonaceae are rarely involved in invasive disease but are frequently associated with colonization or respiratory allergic infection. Trichosporonaceae exhibit intrinsic resistance to echinocandin antimicrobial drugs, posing challenges for treatment and contributing to high mortality rates. We complied a nationwide analysis of 112 cases of invasive disease caused by Trichosporon spp. and related fungi, diagnosed in France over 20 years, that combined clinical data, susceptibility profiles, and molecular identification. We identified 12 species; T. asahii was the most common species recovered, and the new species T. austroamericanum was next. Comparison of clinical data highlighted species and genotypic differences, such as a much higher proportion of children inf

SUBMITTER: Desnos-Ollivier M 

PROVIDER: S-EPMC12870045 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature