Genomic characterization of Neisseria meningitidis from urethritis in a sentinel surveillance hospital, China.

ABSTRACT:

Background

Neisseria meningitidis (Nm) is increasingly being recognized as a novel causative agent of urogenital infections. Recognition of urethritis caused by Nm remains inadequate in China. This study investigates the molecular characterization of Nm isolates cultured from patients with urethritis at a sentinel surveillance hospital in Guangzhou, China from 2022 to 2024.

Methods

Three Nm isolates were cultured from urethral swab samples of consecutive, non-duplicate urethritis cases between 2022 and 2024. Bacterial identification was determined using the VITEK-2 system. Antimicrobial susceptibility testing was performed via the disc diffusion and broth microdilution methods. Whole genome sequencing was conducted using the DNBSEQ platform. Genomic characterization was perf

SUBMITTER: Fu B 

PROVIDER: S-EPMC12870394 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature