An ontology for immune epitopes: application to the design of a broad scope database of immune reactivities.

ABSTRACT:

Background

Epitopes can be defined as the molecular structures bound by specific receptors, which are recognized during immune responses. The Immune Epitope Database and Analysis Resource (IEDB) project will catalog and organize information regarding antibody and T cell epitopes from infectious pathogens, experimental antigens and self-antigens, with a priority on NIAID Category A-C pathogens (http://www2.niaid.nih.gov/Biodefense/bandc_priority.htm) and emerging/re-emerging infectious diseases. Both intrinsic structural and phylogenetic features, as well as information relating to the interactions of the epitopes with the host's immune system will be catalogued.

Description

To effectively represent and communicate the information related to immune epitopes, a formal ontology

SUBMITTER: Sathiamurthy M 

PROVIDER: S-EPMC1287064 | biostudies-literature | 2005 Sep

REPOSITORIES: biostudies-literature