Neonatal brain-age models in full- and preterm infants.

ABSTRACT: Prematurity affects brain development and increases risk for neurodevelopmental impairments. Yet reliable biomarkers for at-risk infants remain limited. The goals of this study are (1a) to construct a white matter neonatal brain-age model including full-term and preterm neonates from a large publicly-available data set, (1b) to evaluate the accuracy of this model for characterizing the preterm brain from the same data set; (2) to determine if a similar model can predict brain-age based on clinical MRI scans from high-risk neonates born preterm; and (3) to evaluate whether this predictive model provides information about the infant's health beyond conventional clinical and demographic measures. We developed brain-age prediction models using diffusion magnetic resonance imaging-derived white

SUBMITTER: Chiu H 

PROVIDER: S-EPMC12871679 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature