Identification and characterization of novel antimicrobial peptides from <i>Camelus dromedarius</i>: a combined bioinformatics and experimental study.

ABSTRACT: There is an urgent need for new antimicrobial agents to address the emerging antimicrobial resistance and the lack of novel antibiotics on the market. Antimicrobial peptides (AMPs) have gained significant interest as potential antibiotics over the past 30 years due to their broad activity against bacteria. So far, the presence, characteristics, and function of AMPs in camel immunity remain to be explored. Therefore, this study aims to identify and functionally characterize AMPs in Camelus Dromedarius using in-silico and experimental approaches. In-silico identification and prediction of cathelicidin peptides properties were conducted using Blastp, Conserved Domain, Signal P-5.0, Peptide Cutter-Expasy, and the Antimicrobial Sequence Scanning System (AMPA) database. Phys

SUBMITTER: Al-Mamari W 

PROVIDER: S-EPMC12872550 | biostudies-literature | 2026

REPOSITORIES: biostudies-literature