Dataset Information
Integrative bioinformatics analysis identifies ubiquitin-related genes and their regulatory networks in hepatoblastoma.
Ontology highlight
ABSTRACT:
SUBMITTER: Wu J
PROVIDER: S-EPMC12872986 | biostudies-literature | 2026 Jan
REPOSITORIES: biostudies-literature
Publications
Integrative bioinformatics analysis identifies ubiquitin-related genes and their regulatory networks in hepatoblastoma.
Discover oncology 20260107 1
BACKGROUND: Hepatoblastoma (HB), the most common pediatric liver malignancy, poses significant challenges in early diagnosis and treatment. To identify ubiquitin-related genes (UbRGs) and signaling pathways involved in HB progression, we analyzed HB-associated gene expression profiles. METHODS: Differential expression analysis was performed on a combined Gene Expression Omnibus dataset integrating two HB datasets (GSE81928 and GSE133039). UbRGs were retrieved from the GeneCards database and the ...[more]