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The hepatitis B care cascade among key populations towards global elimination: a systematic review and meta-analysis.


ABSTRACT:

Background

Key populations bear a disproportionate burden of hepatitis B virus (HBV). We synthesized evidence on the HBV care cascade among key populations to inform strategies toward WHO's 2030 elimination targets.

Methods

We conducted a systematic review and meta-analysis of observational studies published during 2019.01.01-2025.10.31, identified from PubMed, Web of Science, Ovid, and Embase. Eligible studies reported HBV care cascade indicators (vaccination, screening, linkage to care, treatment, adherence, positivity, virological suppression and functional cure) among people living with HIV (PLHIV), men who have sex with men (MSM), female sex workers (FSW), drug users (DU), and detainees across WHO regions. Meta-analysis (PROSPERO CRD42024569607) was performed using gene

SUBMITTER: Su S 

PROVIDER: S-EPMC12874349 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature