Controlled trial of cervical cancer screening frequency among human-papillomavirus-vaccinated women.

ABSTRACT: Cervical screening frequency has not been studied in vaccinees. As the major risk factor, oncogenic human papillomavirus (HPV) is declining due to vaccination. We report a trial to assess the effectiveness of cervical screening frequency among women HPV-vaccinated as early adolescents (NCT02149030). In 2013, 5626 1992-1995-born women, who had received three doses of the HPV16/18 vaccine at ages 12-15 between 2007 and 2010 in a community-randomized vaccination trial (NCT00534638), were allocated at age 22 into high-intensity cytology-based cervical screening by even birth date (Arm A1) or into low-intensity cytology-based cervical screening by odd birth date (Arm A2). One thousand three hundred thirty-three women who received HPV16/18 vaccination at age 18 attended a safety of low intensity

SUBMITTER: Ortega Llobet M 

PROVIDER: S-EPMC12875181 | biostudies-literature | 2026 Apr

REPOSITORIES: biostudies-literature