Unlocking the potential of radiomics in predicting the response of neoadjuvant immunochemotherapy for operable locally advanced esophageal squamous cell carcinoma: a narrative review.

ABSTRACT:

Background and objective

Esophageal squamous cell carcinoma (ESCC) remains a major global health burden, with limited long-term survival despite advances in multimodal therapy. Neoadjuvant immunochemotherapy (NICT) has emerged as a promising preoperative strategy for operable locally advanced ESCC, demonstrating encouraging short-term efficacy and safety profiles. However, substantial interindividual variability in therapeutic response persists, underscoring the need for accurate predictive tools. Radiomics, which extracts high-dimensional quantitative features from medical images, offers a noninvasive means to characterize tumor heterogeneity and predict treatment outcomes. This review aims to synthesize current evidence on the application of radiomics in predicting NICT response

SUBMITTER: Zhao B 

PROVIDER: S-EPMC12875817 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature